The Surprising Vitamin Deficiency Behind Your Chronic Constipation

Tony Kenler
4 min readNov 10, 2023

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Constipation is an increasingly common health complaint, affecting up to 20% of the population. While there are many contributing factors, one major yet overlooked cause is a deficiency in thiamine, also known as vitamin B1.

In a recent informative conversation, a health expert revealed how thiamine deficiency can directly impact nerve function in the digestive tract, leading to compromised movement of food and waste. They explained how the enteric nervous system, sometimes called the "second brain", depends on sufficient thiamine for acetylcholine synthesis and communication between nerves. Without adequate thiamine, peristalsis can slow down or stop altogether, resulting in constipation.

Understanding the Gut-Brain Connection

To comprehend how thiamine deficiency can affect bowel function, it's important to first understand the extensive communication network between the brain and the gut.

The gut has its own intricate nervous system containing over 500 million neurons. This is more than in the entire spinal cord! The vagus nerve connects the brain to the stomach and intestines, shuttling information back and forth. Thiamine plays a crucial role in acetylcholine synthesis, which is needed for vagus nerve signaling.

At the base of the brain is the brain stem, containing the autonomic nervous system that regulates involuntary processes like digestion. Nerves extending from the brain stem heavily rely on thiamine to function properly. Without adequate thiamine, communication signals from the brain to initiate intestinal contractions can be disrupted.

How Thiamine Deficiency Impacts Digestion

When the movement of food through the digestive tract is compromised due to thiamine deficiency, numerous problems can arise including:

- Reduced stomach acid production, necessary for breaking down proteins and killing pathogens
- Impaired signaling between the brain and the vagus nerve, critical for controlling digestive processes
- Delayed emptying of the stomach contents into the small intestine (gastroparesis)
- Sluggish contractions of the gallbladder, resulting in insufficient bile release
- Inadequate pancreatic enzyme secretion needed to digest fats, proteins and carbs
- Slowed peristalsis and muscle contractions in the small and large intestines

Over time, these effects of low thiamine on the digestive process can allow food to stagnate in the intestines, leading to chronic constipation. Studies have found that giving supplemental thiamine to constipation patients improves symptoms.

In addition to constipation, thiamine deficiency can also contribute to small intestinal bacterial overgrowth (SIBO) due to insufficient stomach acid. And when undigested food sits in the colon, it putrefies and releases toxins that may reabsorb and cause damage, a condition called auto-intoxication.

Thiamine’s Role in Diabetes and Nerve Damage

Interestingly, the health expert also pointed out connections between thiamine deficiency and other health conditions.

They explained how frequently eating refined carbohydrates can increase the risk of diabetes. Diabetes is also associated with lower thiamine levels. This combination of high sugar intake and inadequate thiamine appears to be involved in neuropathy, a type of nerve damage often seen in diabetics.

Furthermore, the increasingly prevalent condition gastroparesis, where the stomach digests abnormally slow, is directly linked to both diabetes and thiamine deficiency. This demonstrates the far-reaching effects that low thiamine can have on the nervous system.

Choose Natural Thiamine Supplements

The good news is that thiamine deficiency can often be corrected through supplementation, preferably with natural thiamine as opposed to synthetic forms. When gastrointestinal issues related to low thiamine are resolved, symptoms like constipation, heartburn, and bloating usually improve significantly.

Of course, dietary sources are the best way to obtain thiamine. Whole grains, meat, fish, eggs, legumes, milk, nuts, seeds, oranges and yeast are all high in this essential vitamin. However, the following groups are at increased risk of thiamine deficiency and may benefit from supplementation:

- Alcoholics
- Gastric bypass patients
- Elderly
- Diabetics
- Those with chronic diseases affecting nutrient absorption
- Vegans and vegetarians
- Exclusive breastfed infants over 6 months old

The recommended daily intake for thiamine is:

- Men: 1.2 mg
- Women: 1.1 mg
- Pregnant women: 1.4 mg

Typical doses of thiamine supplements to treat deficiency range from 50-100mg daily, but it’s best to consult a doctor to determine the optimal dosage. Results are often seen quickly, within 1-2 weeks. However, long-standing deficiency may require a longer supplementation period for full resolution.

Other Strategies for Relieving Constipation

While correcting thiamine deficiency is highly beneficial for constipation sufferers, it’s best combined with other lifestyle approaches to maximize relief. Additional strategies include:

- Increasing fiber intake through whole plant foods - fruits, vegetables, beans, nuts and seeds. Fiber helps add bulk to stools and feeds the beneficial gut microbiome.

- Staying well hydrated with at least 8 glasses of water daily. Dehydration can worsen constipation.

- Getting regular exercise, which stimulates contractions in the colon.

- Managing stress levels, as chronic stress impacts bowel function.

- Avoiding dairy products if intolerant, as dairy intolerance is linked with constipation.

For acute constipation, herbal laxatives can provide quick relief when used judiciously. But these should be accompanied by addressing the underlying deficiency or imbalance for lasting results.

Conclusion

A deficiency in thiamine, or vitamin B1, can be a hidden yet significant factor behind chronic constipation, through its detrimental effects on the digestive nervous system. Ensuring adequate thiamine intake through whole food sources and targeted supplementation as needed, along with other lifestyle strategies, can help resolve uncomfortable and frustrating bowel issues. With a multi-pronged approach, most people struggling with constipation can find substantial relief.

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Tony Kenler
Tony Kenler

Written by Tony Kenler

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